科研队伍

学习经历
1990-1994 湖北中医学院 中药系 学士
1998-2001 中国协和医科大学 药物分析 硕士
2005-2008 北京协和医学院 药物分析 博士
工作简历
1994.9-2001.7 北京医学高等专科学校,助教。
2001.9-2005.3 首都医科大学燕京医学院,讲师。
2008.9------ bobapp官方下载 药物晶型研究中心,助研和副研究员。

1、天然产物、药物、药物先导物的三维结构分析
2、药物及先导物的多晶型分析
3、标准物质研制
4、分析化学新技术新方法研究

1. Salt or/and cocrystal? The case of the antidepressant drug venlafaxine, Hongmei Yu, Yong Zhang, Baoxi Zhang, Ying Wang, Li Zhang, Hailu Zhang, Ningbo Gong, Yang Lu, Guanhua Du. CrystEngComm, 2021, 23, 2665-2672
2. Venlafaxine Caffeic Acid Salt: Synthesis, Structural Characterization, and Hypoglycemic Effect Analysis. Hongmei Yu, Yong Zhang, Cheng Xing, Ying Wang, Hailu Zhang, Ningbo Gong, Yang Lu, and Guanhua Du. ACS Omega 2021, 6, 21, 13895-13903
3. Versatile salts as a strategy to modify the biopharmaceutical properties of venlafaxine and potential hypoglycemic effect study, Ningbo Gong, Yong Zhang, Ying Wang, Hongmei Yu, Baoxi Zhang, Hailu Zhang, Yang Lu, Guanhua Du. CRYSTAL GROWTH & DESIGN. 2020, 20, 3131-3139.
4. Control over Polymorph Formation of Polydatin in Binary Solvent System and Structural Characterization, Ningbo Gong, Xue Wang, Ying Wang, Shiying Yang, Junke Song, Yang Lu, Guanhua Du. Journal of Pharmaceutical and Biomedical Analysis, 2020, 189, 113260.
5. Polymorphs and Transformations of the Solid Forms of Organic Salts of 5-Sulfosalicylic Acid and Isonicotinamide. Wenlong Duan, Baokai Liu, Ningbo Gong, Antonino Famulari, and Fang Guo. CRYSTAL GROWTH & DESIGN. 2020. 2020, 20, 12, 7606–7614
6. Crystal structures, dissolution and pharmacokinetic study on a novel phosphodiesterase-4 inhibitor chlorbipram cocrystals. Jianle Zhou, Liang Li, Hailu Zhang, Jiangping Xu, Dandan Huang, Ningbo Gong, Weili Han, Xuemei Yang, Zhengzheng Zhou. International Journal of Pharmaceutics. 2020, 576: 118984.
7. Structure, characterization, solubility and stability of podophyllotoxin Polymorphs. Ningbo Gong, Dezhi Yang, Guimin Jin, Shucong Liu, Guanhua Du, Yang Lu. Journal of Molecular Structure, 2019, 1195, 323-330.
8. Salt formation of two BCS II drugs (indomethacin and naproxen) with (1R, 2R)-1,2-diphenylethylenediamine: Crystal structures, solubility and thermodynamics analysis. Qiang Fu, Hai-Dong Lu, Yi-Fei Xie, Jia-You Liu, Yang Han, Ning-Bo Gong, Fang Guo. Journal of Molecular Structure, 2019, 1185, 281-289.
9. Screening, preparation and characterization of diosgenin versatile solvates. Ningbo Gong,Ying Wang,Baoxi Zhang,Dezhi Yang,Guanhua Du,Yang Lu. Steroids,2019,143, 18-24。
10. Carbamazepine cocrystals with several aromatic carboxylic acids in different stoichiometries: Structures and solid state characterization. Qiang Fu, Yang Han, Yi-fei Xie, Ning-bo Gong, Fang Guo. Journal of Molecular Structure, 2018,1168: 145-152.

1. 实验药理学,编者,高等教育出版社,2021
2. 晶型药物(第二版),编者,人民卫生出版社,2019
3. 天然小分子药物,编者,人民卫生出版社,2018
4. Natural Small Molecule Drugs from Plants,编者,Springer,2018
5. 中药材(毒)古今研究概评,编者,中国医药科技出版社,2018

1. 山奈酚与异烟酰胺共晶物及制备方法和其药物组合物与用途。吕扬 ,杜冠华 ,王英 ,龚宁波 ,杨世颖 。CN109988104A,2019.07.09
2. 虎杖苷晶IV型物质及制备方法和其药物组合物与用途。吕扬 ,杜冠华 ,龚宁波 ,宋俊科 ,杨世颖 。 CN109988203A,2019.07.09
3. 咖啡酸文拉法辛及制备方法和其组合物与用途。 龚宁波, 吕扬, 王英, 喻红梅, 杨世颖。202010590038.4. 2020.6.25

1. 2016。化学药物晶型关键技术体系的建立与应用。杜冠华,吕扬,张 丽,于飞,李明华,汤立达,刘 伟,高肇林,杨世颖,龚宁波。国家科学技术进步奖,二等奖
2. 2014。化学药物晶型关键技术体系的建立与应用。杜冠华,吕扬,张丽,杨世颖,龚宁波,杨德智,何国荣,邢逞,杨庆云,谢平,孙加琳,胡帆,田硕,吴松,宋俊科。北京市科学技术奖,一等奖

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