孔建强，男，博士，研究员，博士生导师，课题组长。主要从事天然药物的生物合成及合成生物学研究。发表文章80余篇，申请专利十余项（授权5项）。《药学学报》，《Acta Pharmaceutica Sinica B》青年编委，《生物工程学报》编委。《Acta Pharmaceutica Sinica B》， 《ACS Synth Biol》,《Microbial cell Fact》，《Bioresource Technology》，《BMC Plant Biology》，《Biochimie》，《Journal of agricultural and food chemistry》，《Phytochemistry》，《药学学报》和《生物工程学报》等三十余种中外期刊的审稿专家。
1，天然产物生物合成
挖掘参与活性天然产物生物合成相关的途径酶基因，并对其进行功能表征；通过计算机模拟以及定向进化等手段对关键途径酶进行突变，获得活性显著提升，具有预设催化特性的生物催化剂，用于天然产物的酶法合成。
2，合成生物学技术制备天然产物
在不同底盘细胞中重构天然产物生物合成代谢途径及调控网络，获得能制备天然产物的细胞工厂，用于天然产物的生物合成。
1, Xue-Ning Wang, Li-Li Hong, and Jian-Qiang Kong*, Diacerein as a promising acyl donor in biosynthetic acetyl-coa and glycosyl esters mediated by a multifunctional maltose O‑acetyltransferase from Escherichia coli, J. Agric. Food Chem, 2021, 69, 6623−6635
2, Li-Li Hong and Jian-Qiang Kong*, Altering the regioselectivity of cytochrome P450 BM3 variant M13 towards genistein through protein engineering and variation of reaction conditions, ACS Omega, 2020, 5, 49, 32059-32066
3, Yan-Li Xu and Jian-Qiang Kong*, OcUGT1-catalyzing glycodiversification of steroids through glucosylation and transglucosylation actions. Molecules 2020, 25, 475.
4, Qing-Wei Chen, Ting-Gong, Pei-Cheng Zhang, Jian-Qiang Kong*, Seven new 1-oxygenated cholestane glycosides from Ornithogalum saundersiae, Journal of Asian Natural Products Research, 2020, 22(3):201-206.
5, Yu-Jia Sun, Jiu-Ming He and Jian-Qiang Kong*, Characterization of two flavonol synthases with iron-independent flavanone 3-hydroxylase activity from Ornithogalum caudatum Jacq, BMC Plant Biology, 2019, 19:195.
6, Qing-Wei Chen, Xu Zhang, Ting Gong, Wan Gao, Shuai Yuan, Pei-Cheng Zhang*, Jian-Qiang Kong*, Structure and bioactivity of cholestane glycosides from the bulbs of Ornithogalum saundersiae Baker. Phytochemistry, 2019, 164: 206-214.
7, Ming Liu, Jian-Qing Kong*, The enzymatic biosynthesis of acylated steroidal glycosides and their cytotoxic activity. Acta Pharmaceutica Sinica B, 2018, 8(6):981-994.
8, Shuai Yuan, Sen Yin, Ming Liu, Jian-Qiang Kong*, Isolation and characterization of a multifunctional flavonoid glycosyltransferase from Ornithogalum caudatum with glycosidase activity. Scientific Reports, 2018, 8, 5886.
9, Shuai Yuan, Sen Yin, Ming Liu, Jiu-Ming He, Jian-Qiang Kong*, OcUGT1-catalyzed glycosylation of testosterone with alternative donor substrates, Process Biochemistry, 2018,73:82-85.
10, Shuai Yuan, Yan Yang, Jian-Qiang Kong*, Biosynthesis of 7,8-dihydroxyflavone glycosides via OcUGT1-catalyzed glycosylation and transglycosylation, Journal of Asian Natural Products Research, 2018, 20(7):662-674.
11, Xin Liu, Jian-Qiang Kong*, Steroids hydroxylation catalyzed by the monooxygenase mutant 139-3 from Bacillus megaterium BM3, Acta Pharmaceutica Sinica B, 2017, 7(4):510–516.
1.孔建强，尹森，一种来源于虎眼万年青的尿苷-5’-二磷酸木糖差向异构酶，其核苷酸序列及应用，ZL201610147497.9，2020年3月31日授权
2.孔建强，尹森，一种来源于虎眼万年青的尿苷-5’-二磷酸半乳糖差向异构酶，其核苷酸序列及应用，ZL201610147498.3，2020年3月31日授权
3.朱平，王伟，孔建强，戴均贵，程克棣，王丽娜，郑晓东，生产紫穗槐-4,11-二烯和青蒿酸的方法，2012，中国，ZL2007101879228
