董毅，博士，副研究员，硕士研究生导师。2014年毕业于北京协和医学院&bobapp官方下载 ，获得药物化学博士学位。2014至2016年在清华大学药学院从事博士后研究工作。2016进入bobapp官方下载 工作至今，先后任助理研究员、副研究员，主要从事创新药物研发、有机合成等方面的工作。近年来，作为项目负责人先后承担了中国博士后面上基金、国家自然科学基金青年项目、医科院“健康长寿”先导专项、国家“十三五”重大新药创制专项（子任务），获得中国药学会科技进步一等奖。近年来发表SCI论文20余篇，其中作为第一作者/通讯作者在Chemical Science, Journal of Medicinal Chemistry, Organic Letters, Chemical Communications, the Journal of Organic Chemistry等杂志发表论文10余篇。申请发明专利2项，授权1项。

1. 趋化因子受体拮抗剂的设计、合成及活性评价
2. 模式识别受体激动剂、拮抗剂的设计、合成、活性评价及相关应用
3. 有机合成方法学研究

1. Y. Dong, X. Zhang, J. Chen, W. Zou, S. Lin, H. Xu*. Switching the site-selectivity of C–H activation in aryl sulfonamides containing strongly coordinating N-heterocycles. Chem. Sci. 2019, 10, 8744−8751 (cover paper). DOI: 10.1039/c9sc03691a
2. Y. Dong, S. Wang, C. Wang, Z. Li, Y. Ma*, G. Liu*. Antagonizing NOD2 signaling with conjugates of paclitaxel and muramyl dipeptide derivatives sensitizes paclitaxel therapy and significantly prevents tumor metastasis. J. Med. Chem. 2017, 60, 1219−1224. DOI: 10.1021/acs.jmedchem.6b01704
3. Y. Dong, J. Chen, Y. Cui, L. Bao, H. Xu*. Cp*RhIII-catalyzed sulfonamide-directed ortho arene C−H carbenoid functionalization with pyridotriazoles. Org. Lett. 2020, 22, 772−775 (cover paper). DOI: 10.1021/acs.orglett.9b03904
4. J. Yang, X. Hu, Z. Liu, X. Li, Y. Dong*, G. Liu*. Cp*CoIII-catalyzed formal [4+2] cycloaddition of benzamides to afford quinazolinone derivatives. Chem. Commun. 2019, 55, 13840−13843. DOI: 10.1039/c9cc07173c
5. Y. Dong, J. Chen, H. Xu*, Rhodium(III)-catalyzed sulfonamide directed ortho C–H carbenoid functionalization via metal carbene migratory insertion. Chem. Commun. 2019, 55, 2027−2030 (cover paper). DOI: 10.1039/c8cc08837c
6. Y. Dong, J. Chen, H. Xu*, Rhodium(III)-catalyzed directed amidation of unactivated C(sp3)–H bonds to afford 1,2-amino alcohol derivatives. Chem. Commun. 2018, 54, 11096−11099 (cover paper). DOI: 10.1039/c8cc05637d
7. Y. Dong, G. Liu*. Auxiliary-assisted palladium-catalyzed direct C(sp3)−H sulfonamidation to afford 1,2-amino alcohol derivatives. J. Org. Chem. 2017, 82, 3864−3872. DOI: 10.1021/acs.joc.6b02975
8. Y. Dong, N. Du, X. Li, L. Zheng, G. Liu*. Tandem chloropalladation/cyclization and dearomative cyclization toward functionalized tricyclic bridged [3.2.1] skeleton compounds. Org. Lett. 2015, 17, 4110−4113. DOI: 10.1021/acs.orglett.5b02076
9. Y. Dong, G. Liu*. Rh-catalyzed sulfonic acid group directed ortho C–H olefination of arenes. Chem. Commun. 2013, 49, 8066−8068. DOI: 10.1039/c3cc44690e