全部论文：
OCRID: https://orcid.org/0000-0002-9567-3763
Github: https://github.com/jwxia2014
代表性论文：
研究方向一：分子信息学与药物设计（计算机化学）
1. Jie Xia#, Zhenyi Wang#, Yi Huan#, Wenjie Xue, Xing Wang, Yuxi Wang, Zhenming Liu, Jui-Hua Hsieh, Liangren Zhang, Song Wu*, Zhu-fang Shen*, Hongmin Zhang*, Xiang Simon Wang*, Pose Filter-based Ensemble Learning Enables Discovery of Orally Active, Nonsteroidal Farnesoid X Receptor Agonists, Journal of Chemical Information and Modeling, 2020, 60(3), 1202-1214.
2. Jie Xia, Terry-Elinor Reid, Song Wu, Liangren Zhang*, Xiang Simon Wang*, Maximal Unbiased Benchmarking Data Sets for Human Chemokine Receptors and Comparative Analysis. Journal of Chemical Information and Modeling, 2018, 58(5):1104-1120
3. Jie Xia, Jui-Hua Hsieh, Huabin Hu, Song Wu*, and Xiang Simon Wang*. The Development of Target-Specific Pose Filter Ensembles To Boost Ligand Enrichment for Structure-Based Virtual Screening, Journal of Chemical Information and Modeling, 2017, 57 (6), 1414–1425
4. Jie Xia, Ermias Lemma Tilahun, Eyob Hailu Kebede, Terry-Elinor Reid, Liangren Zhang*, Xiang Simon Wang*, Comparative modeling and benchmarking data sets for human histone deacetylases and sirtuin families, Journal of Chemical Information and Modeling, 2015, 55(2): 374-388
5. Jie Xia, Hongwei Jin, Zhenming Liu, Liangren Zhang*, Xiang Simon Wang*, An unbiased method to build benchmarking sets for ligand-based virtual screening and its application to GPCRs, Journal of Chemical Information and Modeling, 2014, 54(5): 1433-1450.
6. Shan Li, Yu Ding, Miaomiao Chen, Ya Chen, Johannes Kirchmair, Zihao Zhu, Song Wu, Jie Xia*, HDAC3i-Finder: A machine learning-based computational tool to screen for HDAC3 inhibitors, Molecular Informatics, 2021, 40, 2000105.
7. Jie Xia#, Shan Li#, Yu Ding, Song Wu*, Xiang Simon Wang*, MUBD-DecoyMaker 2.0: A Python GUI application to generate maximal unbiased benchmarking data sets for virtual drug screening, Molecular Informatics,2020,39,1900151
研究方向二：先导结构发现与优化（合成药物化学）
1. Tong Qin#, Xuefeng Gao#, Lei Lei, Jing Feng, Wenxuan Zhang, Yuhua Hu, Zhufang Shen, Zhenming Liu, Yi Huan*, Song Wu*, Jie Xia*, Liangren Zhang, Machine learning- and structure-based discovery of a novel chemotype as FXR agonists for potential treatment of nonalcoholic fatty liver disease. European Journal of Medicinal Chemistry, 2023, 252: 115307.
2. Tong Qin#, Xuefeng Gao#, Lei Lei, Wenxuan Zhang, Jing Feng, Xing Wang, Zhufang Shen, Zhenming Liu, Yi Huan*, Song Wu*, Jie Xia*, Liangren Zhang, Structural optimization and biological evaluation of 1-adamantylcarbonyl-4-phenylpiperazine derivatives as FXR agonists for NAFLD, European Journal of Medicinal Chemistry, 2023, 245: 114903.
3. Wenjie Xue, Xueyao Li, Guixing Ma, Hongmin Zhang, Ya Chen, Johannes Kirchmair, Jie Xia*, Song Wu*, N-Thiadiazole-4-Hydroxy-2-Quinolone-3-Carboxamides Bearing Heteroaromatic Rings as Novel Antibacterial Agents: Design, Synthesis, Biological Evaluation and Target Identification, European Journal of Medicinal Chemistry, 2020 , 188:112022.
4. Xu Lian, Zhonghua Xia, Xueyao Li, Pavel Karpov, Hongwei Jin, Igor V. Tetko, Jie Xia*, Song Wu*, Anti-MRSA Drug Discovery by Ligand-based Virtual Screening and Biological Evaluation, Bioorganic Chemistry, 2021, 114: 105042.
5. Wenjie Xue, Jinlong Tian, Xiang Simon Wang, Jie Xia*, Song Wu*. Discovery of potent PTP1B inhibitors via structure-based drug design, synthesis and in vitro bioassay of Norathyriol derivatives. Bioorganic Chemistry, 2019, 86, 224-234.
