1. Yang Yang , Ke Wang , Hao Chen, Zhiqiang Feng*. Design, synthesis, evaluation, and SAR of 4-phenylindoline derivatives, a novel class of small-molecule inhibitors of the programmed cell death-1/ programmed cell death-ligand 1 (PD-1/PD-L1) interaction. European Journal of Medicinal Chemistry, 211(2021)113001.
2. Hao Chen, Ke Wang, Yang Yang, Xupeng Huang, Xinyan Dai, Zhiqiang Feng*. Design, synthesis, and structure-activity relationship of programmed cell death-1/programmed cell death-ligand 1 interaction inhibitors bearing a benzo[d]isothiazole scaffold. European Journal of Medicinal Chemistry, 217(2021)113377.
3. Xinyan Dai, Ke Wang, Hao Chen, Xupeng Huang, Zhiqiang Feng*. Design, synthesis, and biological evaluation of 1-methyl-1H-pyrazolo [4,3-b]pyridine derivatives as novel small-molecule inhibitors targeting the PD-1/PD-L1 interaction. Bioorganic Chemistry, 114(2021)105034.
4. Ke Wang, Hao Chen, Xinyan Dai, Xupeng Huang, Zhiqiang Feng*. Palladium-Catalyzed One-Pot Synthesis of 2-Substituted Quinazolin-4(3H)-ones from o-Nitrobenzamide and Alcohols. RSC Advances. 11 (2021)13119–13123.
5. Chuan Zhou, Fangfang Lai*, Li Sheng *, Xiaoguang Chen*, Yan Li and Zhiqiang Feng *. Design, Synthesis and Biological Evaluation of Phenyl Urea Derivatives as IDO1 Inhibitors. Molecules, 25(2020), 1447.
6. Lei Lei, Shuainan Liu, Yongqiang Li, Huipeng Song, Lianchao He, Quan Liu, Sujuan Sun,Yan Li, Zhiqiang Feng⁎, Zhufang Shen⁎. The potential role of glucokinase activator SHP289-04 in anti-diabetes and hepatic protection. European Journal of Pharmacology. 2018, 826: 17 −23.
7. Yan Li, Ke Tang, Lijing Zhang, Chao Li, Fei Niu,Wanqi Zhou, Hanze Yang, Zhiqiang Feng*, Xiaoguang Chen*. The molecular mechanisms of a novel multi-kinase inhibitor ZLJ33 in suppressing pancreatic cancer growth. Cancer Letters 356 (2015) 392–403.
8. Lijing Zhang, Yan Li, Ke Wang, Aifang Qin, Xiaoguang Chen*, Zhiqiang Feng*. Synthesis and anti-proliferative activity evaluation of sorafenib derivatives with a 3-arylacryloyl hydrazide unit. Med Chem Res 24:1733–1743 (2015).
9. Yongqiang Li, Kang Tian, Aifang Qin, Lijian Zhang, Lianchao Huo, Lei Lei, Zhufang Shen, Hongrui Song, Zhiqiang Feng*. Discovery of novel urea derivatives as dual-target hypoglycemic agents that activate glucokinase and PPARgamma. European Journal of Medicinal Chemistry, 76(2014): 182-192.
10. Jianxun Lu, Lei Lei, Yi Huan, Yongqiang Li, Lijing Zhang, Zhufang Shen, Wenxiang Hu, Zhiqiang Feng*. Design, synthesis and activity evaluation of the GK/PPARγ dual-target-directed ligands as hypoglycemic agents. ChemMedChem. 9(2014 ) 922-927.
11. Ke Wang, Yan Li, Li-Jing Zhang, Xiao-Guang Chen, Zhi-Qiang Feng*. Synthesis and in vitro cytotoxic activities of sorafenib derivatives. Chinese Chemical Letters. 25(2014), 5, 702-704.
12. Lijian Zhang, KangTian, Yongqiang Li, Lei Lei, Aifang Qin, Lijuan Zhang, Hongrui Song, Lianchao Huo, Lijing Zhang, Xiaofeng Jin, Zhufang Shen, Zhiqiang Feng*, Novel phenyl-urea derivatives as dual-target ligands that can activate both GK and PPARg. Acta Pharmaceutica Sinica B, 2012, 2(6): 588-597.
13. Hui Peng Song, Kang Tian, Lei Lei, Zhu Fang Shen, Shou Xin Liu, Li Juan Zhang, Hong Rui Song, Xiao Feng Jin, Zhi Qiang Feng*. Novel N-(pyrimidin-4-yl)thiazol-2-amine derivatives as dual-action hypoglycemic agents that activate GK and PPARg. Acta Pharmaceutica Sinica B. 1(3) (2011): 166-171.