JIANG Jiandong's Group
Research Interests
1. Metabolic disorders
2. Infectious diseases
3. Cancer
SELECTED PAPERS
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Tumor-selective lipopolyplex encapsulated small active RNA hampers colorectal cancer growth in vitro and in orthotopic murine.
Lu-Lu Wang, Chen-Lin Feng, Wen-Sheng Zheng, Shuai Huang, Wen-Xuan Zhang, Hong-Na Wu, Yun Zhan, Yan-Xing Han, Song Wu, Jian-DongJiang
Biomaterials. 2017; 141:13-28.
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Gut Microbiota-Mediated Personalized Treatment of Hyperlipidemia Using Berberine.
Yan Wang#, Qian Tong, Jia-Wen Shou, Zhen-Xiong Zhao Xiao-Yang Li Xian-Feng Zhang, Shu-Rong Ma, Chi-Yu He, Yuan Lin, Bao-Ying Wen, Fang Guo, Jie Fu, and Jian-Dong Jiang
Theranostics. 2017;7(9):2443-2451.
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TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence.
Ke Li, Feng Wang, Wen-Bin Cao, Xiao-Xi Lv, Fang Hua, Bing Cui, Jiao-Jiao Yu, Xiao-Wei Zhang, Shuang Shang, Shan-Shan Liu, Jin-Mei Yu, Ming-Zhe Han, Bo Huang, Ting-Ting Zhang, Xia Li, Jian-Dong Jiang, Zhuo-Wei Hu.
Cancer Cell. 2017; 31 (5):697-710.e7.
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Gut-brain axis metabolic pathway regulates antidepressant efficacy of albiflorin.
Zhen-Xiong Zhao,* Jie Fu, * Shu-Rong Ma, * Ran Peng, Jin-Bo Yu, Lin Cong, Li-Bin Pan, Zuo-Guang Zhang, Hui Tian, Chun-Tao Che, Yan Wang,# and Jian-Dong Jiang#.
Theranostics. 2018; 8(21):5945-5959.
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Chlorogenic acid effectively treats cancers through induction of cancer cell differentiation.
Shuai Huang, Lu-Lu Wan, Ni-Na Xue,1 Cong Li, Hui-Hui Guo, Tian-Kun Ren, Yun Zhan, Wen-Bing Li, Jie Zhang, Xiao-Guang Chen, Yan-Xing Han,#, Jin-Lan Zhang#, and Jian-Dong Jiang#.
Theranostics. 2019; 9 (23):6745-6763.
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Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases.
Hui-Hui Guo, Chen-Lin Feng, Wen-Xuan Zhang, Zhi-Gang Luo, Hong-Juan Zhang, Ting-Ting Zhang, Chen Ma, Yun Zhan, Rui Li, Song Wu, Zeper Abliz, Cong Li, Xiao-Lin Li, Xiao-Lei Ma, Lu-Lu Wang, Wen-Sheng Zheng, Yan-Xing Han & Jian-Dong Jiang.
Nature Communications 2019; 10 (1):1981.
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Dual‐Stimuli‐Responsive Gut Microbiota‐Targeting Berberine‐CS/PT‐NPs Improved Metabolic Status in Obese Hamsters.
Hui-Hui Guo,Chen Ma,Wen-Sheng Zheng,Yang Luo,Cong Li,Xiao-Lin Li,Xiao-Lei Ma,Chen-Lin Feng,Ting-Ting Zhang,Yan-Xing Han,Zhi-Gang Luo,Yun Zhan,Rui Li,Lu-Lu Wang#, Jian-Dong Jiang#.
Advanced Functional Materials. 2019; 29 (14):1808197.
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The role of the key autophagy kinase ULK1 in hepatocellular carcinoma and its validation as a treatment target.
Si-Tu Ke Li,Yang Gao,Lu-Yao Zhao,Yan Gao,Hong Yi,Jian-Dong Jiang &Zhuo-Rong Li.
Autophagy. 2020 Jan 27;1-15.
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Berberine in the treatment of metabolism-related chronic diseases: A drug cloud (dCloud) effect to target multifactorial disorders.
Wei-Jia Kong, Claudio Vernieri, Jian-Dong Jiang.
Pharmacology & Therapeutics 2020 May;209:107496.